Top 10 Drugs With Greater Health Risks for People Over 60


These medications, used for anxiety or insomnia, may increase the risk of falls, confusion, and cognitive impairment in older adults.

Non-Steroidal Anti-Inflammatory Drugs:

NSAIDs, like ibuprofen, can increase the risk of gastrointestinal bleeding and kidney problems, which may be more pronounced in older individuals.


Opioid medications for pain management can lead to constipation, drowsiness, and an increased risk of falls, especially in older adults.

Anticholinergic Medications:

Some medications with anticholinergic effects  may contribute to cognitive decline and increase the risk of falls.

Proton Pump Inhibitors (PPIs):

Long-term use of PPIs, commonly used to treat acid reflux, may increase the risk of fractures and certain nutritional deficiencies.


While statins are generally well-tolerated, they may have a higher risk of muscle-related side effects in some older individuals.


Blood thinners, used to prevent blood clots, may increase the risk of bleeding, and monitoring is crucial, especially in older adults.

Diabetes Medications:

Some medications for diabetes may need adjustment in older individuals due to changes in kidney function and the risk of hypoglycemia.

Antiplatelet Medications:

Medications like aspirin may increase the risk of bleeding and require careful consideration in the elderly.


Long-term use of corticosteroids can lead to bone loss, increased risk of infections, and other adverse effects.